Antibiotic Sodium Acetate Trihydrate
CAS NO.: 6131-90-4
Molecular Formula: CH3COONa·3H2O
Molecular Weight: 136.08
Character: Colorless crystal, it is soluble in water and alcohol and lightly soluble in acetic acid; specific gravity:1.45; melting point: 58℃.
Usage:It should be stored in a dry and ventilative warehouse, kept away from heat and moisture during transportation, unloaded with care so as to avoid damage. Furthermore, it must be stored separately from poisonous substances.
Package: 25kg plastic woven bag or 1000kg Ton-bag
Storage: It should be stored in a dry and ventilative warehouse, kept away from heat and moisture during transportation, unloaded with care so as to avoid damage. Furthermore, it must be stored separately from poisonous substances.
- Product Description
Antibiotic Sodium Acetate Trihydrate - Pharmaceutical Grade Buffer & pH Regulator
When your antibiotic production demands precision and purity, Antibiotic Sodium Acetate Trihydrate from Shanxi Zhaoyi Chemical delivers exceptional performance. Manufactured since 1988 in our 27,000 m² GMP-compliant facility, our pharmaceutical-grade product achieves ≥99.5% purity with chloride content ≤0.001% and heavy metals ≤0.0003%.
With an annual production capacity of 150,000 tons and strict compliance with USP/EP standards, we ensure consistent quality for penicillin, cephalosporin, and quinolone synthesis. Our trihydrate crystal maintains a stable 136.08 molecular weight with melting point at 58℃, providing reliable pH buffering (7.5-9.0) that optimizes your antibiotic yields while reducing purification costs.
Key Features & Benefits
Our item offers pharmaceutical producers basic preferences in anti-microbial union. The ultra-low debasement profile decreases downstream refinement costs whereas quickening your generation timeline.
As an compelling acid-binding specialist, it neutralizes union by-products and expands catalyst benefit life. Your response situations stay steady, avoiding middle of the road deterioration amid capacity and guaranteeing generation continuity.
The product's predominant buffering capacity keeps up ideal pH ranges all through union cycles. You'll involvement progressed anti-microbial yields, upgraded virtue levels, and total compatibility with standard amalgamation crude materials and catalysts without presenting destructive contaminants.
Technical Specifications
Parameter | Specification | Test Method |
Content (CH₃COONa·3H₂O) | ≥99.5% | USP/EP |
pH (5% solution) | 7.5-9.0 | Potentiometric |
Clarity Test | Qualified | Visual |
Water Insoluble | ≤0.005% | Gravimetric |
Chloride (Cl) | ≤0.001% | Argentometric |
Sulfate (SO₄) | ≤0.005% | Turbidimetric |
Phosphate (PO₄) | ≤0.0005% | Spectrophotometric |
Magnesium (Mg) | ≤0.001% | AAS |
Calcium (Ca) | ≤0.025% | AAS |
Iron (Fe) | ≤0.0003% | Colorimetric |
Lead (Pb) | ≤0.001% | ICP-MS |
Arsenic (As) | ≤0.0002% | ICP-MS |
Readily Oxidizable Substance | Qualified | Permanganate test |
Molecular Weight | 136.08 g/mol | Calculated |
Melting Point | 58℃ | Capillary method |
Specific Gravity | 1.45 | Pycnometer |
How It Works?
Our pharmaceutical-grade sodium acetate trihydrate functions through multiple mechanisms in antibiotic production. When dissolved in your synthesis medium, it immediately begins regulating pH levels through its buffering capacity.
The acetate ions neutralize acidic by-products generated during antibiotic synthesis reactions. This acid-binding action drives reactions forward while protecting sensitive catalysts from acid degradation.
You'll notice the stable crystal structure maintains three water molecules per sodium acetate unit. This hydration state ensures consistent solubility and predictable reaction kinetics across production batches, giving you reproducible results every time.
Our Factory
30-YEAR ACETATE SPECIALIST | Non-caking, High Purity, Global Supply Chain



Applications
Anti-microbial Synthesis: Our item serves as the essential pH controller in penicillin, cephalosporin, macrolide, and quinolone generation lines. It optimizes response situations for most extreme yield.
Buffer Systems: Formulate steady pharmaceutical buffer arrangements for anti-microbial halfway capacity and decontamination forms. The 7.5-9.0 pH run gives great stability.
Hemodialysis Concentrates: Use in renal dialysis details where acetic acid derivation particles metabolize into bicarbonate, successfully overseeing metabolic acidosis in patients.
Injectable Preparations: Incorporate into parenteral anti-microbial details requiring exact pH control and ultra-low endotoxin levels.






Antibiotic Sodium Acetate Trihydrate vs Other Products
Feature | Our Pharma Grade | Technical Grade | Food Grade | Anhydrous Form |
Purity | ≥99.5% | 58-60% | ≥99.0% | ≥99.0% |
Chloride Content | ≤0.001% | ≤0.035% | ≤0.01% | ≤0.01% |
Heavy Metals | ≤0.0003% | ≤0.002% | ≤0.001% | ≤0.001% |
Lead (Pb) | ≤0.001% | ≤0.005% | ≤0.002% | ≤0.002% |
GMP Compliance | Yes | No | Partial | Varies |
Bioburden Control | Strict | None | Moderate | Moderate |
Water Content | Stable 3H₂O | Variable | Stable 3H₂O | 0% (anhydrous) |
Antibiotic Suitability | Optimal | Not suitable | Limited | Requires recalculation |
Price Point | Premium | Economy | Mid-range | Premium |
Storage Stability | 2-3 years | 1-2 years | 2 years | 3+ years |
Certifications & Compliance
Shanxi Zhaoyi Chemical maintains rigorous quality standards recognized globally. Our manufacturing facility holds ISO certification, ensuring consistent quality management throughout production.
We've achieved KOSHER and HALAL certifications, enabling you to serve diverse global markets. Our Antibiotic Sodium Acetate Trihydrate meets USP (United States Pharmacopeia) and EP (European Pharmacopoeia) monograph requirements.
All batches undergo comprehensive testing before release. We maintain documentation supporting Drug Master File (DMF) references and can provide Certificates of Analysis (CoA) with every shipment.






Packaging Options
Standard Packaging: 25kg plastic woven bags with double polyethylene liners protect your product from moisture during storage and transportation.
Bulk Packaging: 1000kg ton-bags available for high-volume pharmaceutical manufacturers seeking cost efficiency and streamlined logistics.
All packaging materials comply with pharmaceutical-grade requirements. We seal containers to maintain relative humidity below 60%, preventing efflorescing or deliquescing that could affect product performance.
Custom packaging solutions available upon request to meet your specific production requirements and storage conditions.
Packing

Manufacturing Process
Our generation starts with high-purity crude materials sourced through qualified sellers. We conduct approaching fabric review guaranteeing details meet our exacting requirements.
The union happens in committed GMP-certified generation zones with natural checking. Controlled crystallization forms surrender the steady trihydrate frame with exact water content.
Multi-stage decontamination expels follow metals, chlorides, and sulfates to pharmaceutical-grade levels. Your item experiences thorough quality testing at different checkpoints all through manufacturing.
Final processing and screening guarantee steady molecule estimate conveyance. We bundle quickly after quality endorsement in our controlled-environment bundling office to keep up item keenness.
Shipment



Why Choose Us?
Decades of Expertise: Since 1988, we've culminated acetic acid derivation generation with 35+ a long time of specialized fabricating information. You advantage from our collected handle optimization and quality insights.
Massive Generation Capacity: Our 150,000-ton yearly capacity guarantees dependable supply indeed amid top request. You'll never confront generation delays due to fabric shortages.
Global Advertise Presence: We trade to Europe, America, and Asia, understanding different administrative prerequisites. Your compliance concerns are tended to through our worldwide experience.
Customer-Centric Service: We react to specialized request inside 24 hours, giving application direction and investigating bolster. Free tests offer assistance you confirm item appropriateness some time recently commitment.
Quality Guarantee: We acknowledge unlimited returns if items do not meet your anti-microbial generation prerequisites. Our commitment to your victory drives each commerce choice.
FAQ
Q: What recognizes pharmaceutical review from specialized review sodium acetic acid derivation trihydrate?
A: Pharmaceutical review experiences GMP fabricating with strict control over endotoxins, follow metals, and bioburden. Specialized review contains higher debasements unacceptable for human parenteral applications. Our item meets USP/EP infusion standards.
Q: How ought to I store this item to keep up stability?
A: Store in hermetically sealed holders inside a cool, dry stockroom at relative mugginess underneath 60%. Keep absent from solid oxidizers and acids. Commonplace rack life comes to 2-3 a long time beneath legitimate conditions.
Q: Can this be utilized in hemodialysis formulations?
A: Completely. It's broadly utilized in dialysis concentrates where acetic acid derivation particles metabolize into bicarbonate, buffering metabolic acidosis. Our hemodialysis-grade determinations cover with antibiotic-grade endotoxin requirements.
Q: What's your lead time for bulk orders?
A: We keep up vital stock levels based on client generation plans. Ordinary lead time ranges 7-15 days for holder loads, guaranteeing your anti-microbial generation proceeds uninterrupted.
Q: Do you give administrative bolster documentation?
A: Yes. We supply Certificates of Examination, steadiness information, and documentation supporting Sedate Ace Record references. Our quality group helps with administrative filings as required.
Request a Quote
Ready to elevate your antibiotic production quality with Antibiotic Sodium Acetate Trihydrate? Contact us today for competitive pricing and free sample testing. Email: sxzy@sxzhaoyi.com.
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