Pharmaceutical Intermediate Sodium Acetate Trihydrate
CAS NO.: 6131-90-4
Molecular Formula: CH3COONa·3H2O
Molecular Weight: 136.08
Character: Colorless crystal, it is soluble in water and alcohol and lightly soluble in acetic acid; specific gravity:1.45; melting point: 58℃.
Usage:It should be stored in a dry and ventilative warehouse, kept away from heat and moisture during transportation, unloaded with care so as to avoid damage. Furthermore, it must be stored separately from poisonous substances.
Package: 25kg plastic woven bag or 1000kg Ton-bag
Storage: It should be stored in a dry and ventilative warehouse, kept away from heat and moisture during transportation, unloaded with care so as to avoid damage. Furthermore, it must be stored separately from poisonous substances.
- Product Description
Pharmaceutical Intermediate Sodium Acetate Trihydrate - Premium Grade from SHANXI ZHAOYI CHEMICAL
SHANXI ZHAOYI CHEMICAL CO., LTD brings you pharmaceutical-grade Sodium Acetate Trihydrate with exceptional purity ≥99.5%, specifically engineered for pharmaceutical intermediate synthesis. Our product features strictly controlled impurities with chloride content ≤0.001% and heavy metals ≤0.0003%, ensuring superior reaction performance. Backed by 35+ years of manufacturing expertise since 1988, our facility produces 150,000 tons annually across a 27,000 m² production base. This Pharmaceutical Intermediate Sodium Acetate Trihydrate (CAS NO. 6131-90-4) delivers consistent batch-to-batch quality with molecular weight 136.08 and optimal water solubility. With ISO, KOSHER, and HALAL certifications, our colorless crystalline product maintains stable performance at melting point 58℃ and specific gravity 1.45, making it your reliable choice for critical pharmaceutical applications.
Key Features & Benefits
Our pharmaceutical-grade sodium acetic acid derivation trihydrate offers remarkable virtue that kills common industry challenges. You'll involvement steady union comes about with each clump, much appreciated to our thorough quality control protocols.
The ultra-low dampness substance guarantees unsurprising response selectivity and maximized item surrender. Your blend forms advantage from great water dissolvability, empowering uniform scattering all through response frameworks without undesirable by-products.
We've outlined this item particularly for pharmaceutical middle applications. You can depend on its tall response action and compatibility with different chemical crude materials, streamlining your generation workflow and diminishing filtration steps.
Technical Specifications
Parameter | Specification | Test Method |
Content (CH3COONa·3H2O) | ≥99.5% | USP Standard |
pH Value | 7.5-9.0 | pH Meter |
Clarity Test | Qualified | Visual Inspection |
Water Insoluble | ≤0.005% | Gravimetric |
Chloride (Cl) | ≤0.001% | Titration |
Sulfate (SO4) | ≤0.005% | Turbidimetric |
Phosphate (PO4) | ≤0.0005% | Spectrophotometry |
Magnesium (Mg) | ≤0.001% | AAS |
Calcium (Ca) | ≤0.025% | AAS |
Ferrum (Fe) | ≤0.0003% | Colorimetric |
Lead (Pb) | ≤0.001% | AAS |
Arsenic (As) | ≤0.0002% | AAS |
Readily Oxidizable Substance | Qualified | Titration |
Molecular Formula | CH3COONa·3H2O | - |
Molecular Weight | 136.08 | - |
Appearance | Colorless Crystal | - |
Specific Gravity | 1.45 | Density Meter |
Melting Point | 58℃ | DSC |
How It Works?
Sodium acetic acid derivation trihydrate capacities as a flexible building square in pharmaceutical union. When you present it into your response frameworks, it acts as a buffering specialist, keeping up ideal pH levels all through complex chemical processes.
The acetic acid derivation particle partakes specifically in blend responses as a nucleophile or clearing out bunch. Its trihydrate frame gives controlled water substance, which can be significant for particular response instruments requiring hydration.
In buffer arrangements, our item stabilizes pH between 7.5-9.0, securing touchy pharmaceutical intermediates from corruption. The sodium cation remains generally dormant, whereas the acetic acid derivation component drives your wanted chemical changes with exactness and unwavering quality.
Our Factory
30-YEAR ACETATE SPECIALIST | Non-caking, High Purity, Global Supply Chain



Applications
Pharmaceutical Union: You can utilize this item as a key reagent in fabricating dynamic pharmaceutical fixings (APIs) and complex intermediates. It serves superbly in acetylation responses and as a buffering component.
Buffer Planning: Your research facility will advantage from its utilize in making pharmaceutical-grade buffer arrangements. It keeps up steady pH conditions fundamental for protein responses and protein stabilization amid medicate formulation.
Crystallization Forms: The item helps in crystallizing pharmaceutical compounds, progressing virtue and molecule estimate dispersion. You'll accomplish superior control over your last item characteristics.
Quality Control Benchmarks: Expository research facilities utilize it as a reference standard for testing and approval strategies, guaranteeing compliance with pharmacopeial prerequisites all through your generation chain.






Pharmaceutical Intermediate Sodium Acetate Trihydrate vs Other Products
Feature | Our Pharmaceutical Grade | Industrial Grade | Food Grade | Competitor Pharma Grade |
Purity (%) | ≥99.5 | ≥98.0 | ≥99.0 | ≥99.0 |
Chloride Content (%) | ≤0.001 | ≤0.1 | ≤0.01 | ≤0.005 |
Heavy Metal (Fe) (%) | ≤0.0003 | ≤0.005 | ≤0.001 | ≤0.0005 |
Lead (Pb) (%) | ≤0.001 | ≤0.005 | ≤0.002 | ≤0.001 |
Arsenic (As) (%) | ≤0.0002 | ≤0.001 | ≤0.0003 | ≤0.0003 |
Batch Consistency | Excellent | Variable | Good | Good |
Moisture Control | Strictly Controlled | Standard | Standard | Controlled |
Certifications | ISO/KOSHER/HALAL | Basic | Food Safety | ISO |
Technical Support | 24-Hour Response | Limited | Limited | Standard |
Supply Capacity (tons/year) | 150,000 | Varies | Varies | Lower |
Price Competitiveness | Optimal | Lower | Medium | Higher |
Certifications & Compliance
SHANXI ZHAOYI CHEMICAL maintains rigorous quality standards through internationally recognized certifications. Our Pharmaceutical Intermediate Sodium Acetate Trihydrate production facility holds ISO certification, ensuring consistent quality management throughout manufacturing processes.
We've earned KOSHER and HALAL certifications, expanding the applications where you can confidently use our product. These credentials demonstrate our commitment to meeting diverse regulatory requirements across global markets.
Our manufacturing processes comply with Good Manufacturing Practice (GMP) guidelines. Every batch undergoes comprehensive testing before release, and we maintain complete traceability documentation to support your regulatory submissions and audits.






Packaging Options
We offer adaptable bundling arrangements custom-made to your generation scale and taking care of inclinations. Our standard choice incorporates 25kg plastic woven sacks with pharmaceutical-grade inward liners, giving great dampness assurance and simple handling.
For bulk operations, you can select our 1000kg ton-bags, which diminish bundling squander and streamline coordinations. These enormous packs include food-grade development with secure closures to keep up item judgment amid capacity and transport.
Custom bundling setups are accessible upon ask. We can give aluminum-plastic composite sacks or fixed plastic barrels for upgraded dampness assurance in sticky situations, guaranteeing your sodium acetic acid derivation trihydrate arrives in culminate condition.
Packing

Manufacturing Process
Our generation starts with high-purity crude fabric determination. We source premium-grade acidic corrosive and sodium compounds, subjecting each fixing to thorough approaching quality control testing some time recently processing.
The blend happens in controlled-environment reactors where temperature, weight, and pH are ceaselessly observed. Crystallization takes put beneath carefully overseen conditions to accomplish ideal gem structure and immaculateness levels surpassing 99.5%.
After crystallization, your item experiences different filtration stages. We utilize progressed filtration, washing, and drying strategies to evacuate debasements whereas protecting the trihydrate shape. Last bundling happens in cleanroom conditions to avoid contamination.
Quality affirmation testing happens at each organize. Our research facility conducts comprehensive investigation utilizing spectrophotometry, titration, and nuclear assimilation spectroscopy, guaranteeing each parameter meets pharmaceutical middle details some time recently expedite.
Shipment



Why Choose Us?
With over 35 years of acetate manufacturing expertise since 1988, we've refined our processes to deliver unmatched quality. You benefit from our deep understanding of pharmaceutical intermediate requirements and industry best practices.
Our 150,000-ton annual production capacity ensures reliable supply continuity for your operations. We maintain strategic inventory levels, guaranteeing on-time delivery even during peak demand periods without compromising quality.
You'll receive dedicated technical support with 24-hour response times. Our experienced team helps optimize your synthesis processes, recommends appropriate handling procedures, and troubleshoots any application challenges you encounter.
We offer competitive pricing without sacrificing quality. Our large-scale operations and efficient manufacturing processes enable cost savings that we pass directly to you, improving your production economics.
FAQ
Q: How does your item guarantee batch-to-batch consistency?
A: We execute strict quality control conventions at each generation organize. Each clump experiences indistinguishable testing strategies taking after standardized strategies, and we keep up point by point prepare parameters to guarantee reproducible comes about that meet pharmaceutical middle union requirements.
Q: What is the ordinary lead time for bulk orders?
A: Standard conveyance happens inside 15-20 days for amounts up to 100 tons. We keep up key stock and can orchestrate sped up shipping for pressing necessities. Contact us with your particular volume needs for precise scheduling.
Q: Can you give tests for compatibility testing?
A: Yes, we offer free small-batch tests to offer assistance you confirm item appropriateness for your amalgamation forms. Basically reach out with your application subtle elements, and we'll orchestrate provoke test conveyance with total specialized documentation.
Q: What documentation do you give with shipments?
A: Each arrange incorporates Certificate of Investigation (CoA), Fabric Security Information Sheet (MSDS), and pertinent certification reports. We can supply extra administrative documentation such as Medicate Ace Records (DMF) back materials upon request.
Q: How ought to I handle the item if bundling is harmed amid transit?
A: Review all bundling promptly upon receipt. If harm happens, photo it and contact us inside 24 hours. We'll organize substitution shipment and work with carriers to resolve the issue without disturbing your generation schedule.
Q: Is your sodium acetic acid derivation trihydrate consistent with natural solvents?
A: Our item appears great solvency in water and liquor, with slight solvency in acidic corrosive. For particular natural dissolvable compatibility questions related to your amalgamation handle, our specialized group can give point by point direction based on your prerequisites.
Q: What quality guarantees do you offer?
A: We guarantee all specifications listed in our technical documentation. If any batch fails to meet pharmaceutical intermediate synthesis requirements, we offer unconditional returns or replacements. Our commitment to quality is backed by comprehensive testing and certification.
Q: How long can I store the product after opening?
A: Once opened, we recommend using the product within 24 hours or resealing immediately in moisture-proof containers. Proper resealing can extend usability, but we suggest storing opened packages in environments with relative humidity ≤65% to prevent moisture absorption.
Request a Quote
Ready to elevate your pharmaceutical synthesis with Pharmaceutical Intermediate Sodium Acetate Trihydrate? Email us at sxzy@sxzhaoyi.com now.
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