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Pharmaceutical Intermediate Sodium Acetate Anhydrous

Product Name: Pharmaceutical Intermediate Sodium Acetate Anhydrous
CAS NO.: 127-09-3
Molecular Formula: CH3COONa
Molecular Weight: 82.03
Character: white crystal powder; specific gravity is 1.528 and melting point is 324℃.
Usage: It is a kind of chemical raw material and is widely used in dye, pharmaceutical, chemical reagent fields, sewagement and etc.
Package: 25kg plastic woven bag or 1000kg Ton-bag
Storage: It should be stored in a dry and ventilative warehouse, kept away from heat and moisture during transportation, unloaded with care so as to avoid damage. Furthermore, it must be stored separately from poisonous substances.
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  • Product Description

Pharmaceutical Intermediate Sodium Acetate Anhydrous - High-Purity Chemical Raw Material

SHANXI ZHAOYI CHEMICAL CO., LTD brings you premium-grade Pharmaceutical Intermediate Sodium Acetate Anhydrous manufactured with three decades of expertise since 1988. Our product delivers ≥99.0% purity with exceptionally low impurity levels: Fe ≤0.0005%, heavy metals (as Pb) ≤0.002%, and moisture content <0.1%.

Produced in our 27,000 m² facility with 150,000 tons annual capacity, this white crystalline powder (molecular weight 82.03, melting point 324℃) serves as a critical component in pharmaceutical synthesis. Our pharmaceutical-grade material features controlled pH (7.5-9.2) and passes ISO, KOSHER, and HALAL certifications. The anhydrous form provides superior reactivity per kilogram compared to hydrate versions, making it ideal for water-sensitive reactions in drug intermediate production.

Key Features & Benefits

Our anhydrous sodium acetic acid derivation offers particular preferences for pharmaceutical fabricating. You'll advantage from its high-density acetic acid derivation particle concentration, which maximizes response effectiveness whereas decreasing coordinations costs.

The ultra-low debasement profile minimizes downstream decontamination costs. With chloride substance ≤0.002% and sulfate ≤0.01%, you can keep up exacting pharmaceutical quality measures all through your union process.

Its hygroscopic however free-flowing crystalline structure guarantees reliable dealing with. The item breaks up promptly in water (119 g/100 ml at 0°C), giving unsurprising execution in your formulations.

You pick up fabulous buffering capacity over pH 7.5-9.0 extend. This steadiness makes a difference you control response situations accurately, boosting abdicate and virtue of your target intermediates.

The anhydrous characteristic disposes of impedances with moisture-sensitive responses. You can continue unquestionably with unions requiring strict water control without compromising selectivity.

Technical Specifications

Parameter
Specification
Content (CH3COONa)
≥99.0%
Molecular Formula
CH3COONa
Molecular Weight
82.03
CAS Number
127-09-3
Appearance
White crystal powder
Specific Gravity
1.528
Melting Point
324℃
pH (5% solution)
7.5-9.2
Clarity Test
Qualified
Water Insoluble
≤0.01%
Chloride (Cl)
≤0.002%
Sulfate (SO4)
≤0.01%
Phosphate (PO4)
≤0.001%
Magnesium (Mg)
≤0.002%
Calcium (Ca)
≤0.05%
Ferrum (Fe)
≤0.0005%
Heavy Metal (as Pb)
≤0.002%

How It Works?

This compound capacities through different components in pharmaceutical blend. As a pH controller, it keeps up ideal soluble conditions between 7.5-9.0, making the perfect environment for your chemical responses to continue efficiently.

Acting as an acid-binding specialist, it neutralizes acids produced amid union. This neutralization drives responses forward whereas minimizing undesirable side responses that seem compromise your item quality.

The acetic acid derivation particle partakes specifically in certain blend pathways. It can serve as a nucleophile, catalyst, or reactant depending on your particular middle of the road generation requirements.

Its buffering activity stabilizes response frameworks against pH changes. You'll involvement more reproducible comes about bunch after group, decreasing inconstancy in your fabricating process.

The anhydrous nature avoids hydrolysis of water-sensitive intermediates. This security guarantees your important beginning materials change over effectively to wanted items without corruption.

 
Our Factory
 

30-YEAR ACETATE SPECIALIST | Non-caking, High Purity, Global Supply Chain

our factory
our factory
factory workshop
factory workshop
our laboratory
our laboratory

Applications

You'll discover this fabric vital in anti-microbial middle of the road amalgamation. In cephalosporin generation, including 1.2% can increment response abdicate by 12%-18%, specifically moving forward your generation economics.

Chemical sedate middle of the road fabricating benefits from its tall virtue. Whether synthesizing cardiovascular drugs, analgesics, or other restorative compounds, you pick up steady quality that meets administrative standards.

Biological sedate middle of the road generation requires remarkable immaculateness levels. Our pharmaceutical-grade fabric conveys the contamination-free execution you require for touchy bioprocessing applications.

It capacities perfectly as a engineered crude fabric in complex multi-step forms. You can consolidate it at different stages where acetic acid derivation chemistry plays a part in building atomic complexity.

The compound serves as an compelling catalyst in acetylation responses. Your esterification and acylation forms will continue easily with legitimate catalytic movement and selectivity.

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Connecting the World - Dialogue with Global Clients
 
Connecting the World
 
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Pharmaceutical Intermediate Sodium Acetate Anhydrous vs Other Products

Feature
Our Anhydrous Grade
Standard Industrial Grade
Trihydrate Form
Purity (CH3COONa)
≥99.0%
98.0-98.5%
Lower effective content
Heavy Metals (Pb)
≤0.002%
≤0.005%
≤0.005%
Iron (Fe)
≤0.0005%
≤0.002%
≤0.002%
Water Content
<0.1%
0.5-2.0%
~39% (crystal water)
Active Ion Density
Highest
Medium
Lowest per kg
Water-Sensitive Compatibility
Excellent
Fair
Poor
Pharmaceutical Certification
ISO/KOSHER/HALAL
Limited
Varies
Price per Active Unit
Competitive
Lower absolute price
Highest logistics cost

Certifications & Compliance

Our fabricating office keeps up ISO certification, guaranteeing precise quality administration all through generation. You get items made beneath universally recognized quality frameworks.

KOSHER certification approves our forms meet strict dietary and immaculateness measures. This certification illustrates our commitment to thorough fabricating controls that advantage all pharmaceutical applications.

HALAL certification gives extra confirmation of quality and moral generation hones. These different certifications reflect our commitment to serving different worldwide markets with steady excellence.

Our items comply with significant pharmaceutical industry benchmarks. We back third-party testing and give comprehensive documentation for your administrative recording needs.

Certification Certificate
 
Certification Certificate
 
Certification Certificate
 
Certification Certificate
 
Certification Certificate
 
Certification Certificate
 

Packaging Options

We offer flexible packaging to suit your volume requirements. Standard 25kg plastic woven bags provide convenient handling for regular production batches, with excellent moisture barrier properties.

For larger operations, 1000kg ton-bags deliver economies of scale. These bulk packages reduce handling frequency while maintaining product integrity through specialized moisture-resistant construction.

All packaging features rigorous sealing to protect the hygroscopic material. You'll receive product in optimal condition, preserving the <0.1% moisture specification throughout storage and transport.

Custom packaging solutions are available upon request. We can accommodate specific requirements for your facility's material handling systems and storage configurations.

 
Packing
 

Packing

Manufacturing Process

Our production begins with high-purity raw materials sourced through qualified supply chains. Strict incoming quality control ensures only materials meeting our standards enter the manufacturing process.

The synthesis process employs controlled neutralization reactions under precise temperature and pH monitoring. This control delivers consistent product quality batch after batch.

Crystallization occurs under carefully managed conditions to achieve optimal particle size distribution. You benefit from free-flowing powder that handles predictably in your equipment.

Multi-stage purification removes trace impurities to pharmaceutical-grade levels. Our rigorous filtration and washing protocols ensure Fe, Pb, and other contaminants remain well below specification limits.

Final drying under controlled humidity conditions removes moisture to <0.1%. This critical step ensures the Pharmaceutical Intermediate Sodium Acetate Anhydrous characteristic that distinguishes our product for water-sensitive applications.

Comprehensive quality testing validates every batch before release. We perform full specification analysis and retain samples for traceability and ongoing quality assurance.

 
Shipment
 
Maritime Transport
Maritime Transport
Air transport
Air transport
Land transportation​
Land transportation​

Why Choose Us?

With 36 a long time of fabricating encounter since 1988, we bring unmatched industry information to your supply chain. Our life span illustrates steady unwavering quality that pharmaceutical producers require.

Our 150,000-ton yearly capacity guarantees steady supply indeed for large-volume contracts. You won't confront assignment deficiencies or supply disturbances that might affect your generation schedules.

We serve clients over Europe, America, and Asia with demonstrated worldwide coordinations skill. Our trade involvement implies smooth documentation and solid conveyance to your office worldwide.

Customer fulfillment drives our trade logic. We give specialized bolster for measurement optimization, making a difference you accomplish 12%-18% surrender enhancements in applications like cephalosporin synthesis.

Our coordinates acetic acid derivation item portfolio offers one-stop sourcing comfort. Past sodium acetic acid derivation anhydrous, we supply related materials for your comprehensive chemical obtainment needs.

Quality administration frameworks guarantee batch-to-batch consistency. You can create your forms unquestionably knowing future shipments will perform indistinguishably to your capability bunches.

Our Customer

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FAQ

Q: What is the recommended addition ratio in cephalosporin intermediate synthesis?

A: The addition ratio typically ranges from 0.5%-2.0% of total reaction system weight. In cephalosporin synthesis specifically, 1.2% addition can increase reaction yield by 12%-18%. We recommend conducting small-scale tests to optimize the ratio for your specific process, and our technical team can provide support during this optimization.

Q: How should I store this product?

A: Store in a dry, well-ventilated warehouse away from heat and moisture. The hygroscopic nature requires sealed containers to maintain the <0.1% moisture specification. Keep separate from incompatible substances, and handle containers carefully during transport to avoid damage.

Q: What distinguishes anhydrous from trihydrate form?

A: The anhydrous form contains <0.1% water versus ~39% crystal water in trihydrate. This provides higher active acetate ion density per kilogram, reducing logistics costs and improving reactivity. Anhydrous form is essential for water-sensitive reactions where trihydrate would introduce unwanted moisture.

Q: Can you provide technical support for process optimization?

A: Yes, our technical team offers guidance on dosage optimization and application troubleshooting. We help you determine optimal addition ratios through small-scale testing protocols and can advise on pH control strategies for your specific intermediate synthesis.

Q: What documentation do you provide for regulatory compliance?

A: We supply Certificate of Analysis (CoA) for each batch, showing full specification compliance. Material Safety Data Sheets (MSDS), ISO/KOSHER/HALAL certificates, and other regulatory documentation are available. We support your audits and regulatory filing requirements with comprehensive traceability records.

Q: What is your minimum order quantity?

A: We accommodate various order sizes from trial quantities to bulk contracts. Contact us to discuss your volume requirements and we'll propose appropriate packaging and delivery arrangements that match your production needs.

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Ready to enhance your pharmaceutical intermediate synthesis with Pharmaceutical Intermediate Sodium Acetate Anhydrous? Email: sxzy@sxzhaoyi.com

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